Time strata | Random sequence generation (n = 384) | Allocation concealment (n = 399) | Blinding participants and personnel (n = 137) | Blinding outcome assessment (n = 130) | Blinding (n = 227) | Incomplete outcome data (n = 345) | Selective reporting (n = 337) | Other bias (n = 273) |
---|---|---|---|---|---|---|---|---|
<1990 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
1990–1995 | 1.17 (0.58–2.35) | 0.74 (0.34–1.62) | 1.29 (0.48–3.50) | 0.71 (0.26–2.00) | 1.12 (0.44–2.84) | 0.49 (0.24–0.99) | 1.13 (0.56–2.26) | 1.10 (0.49–2.49) |
1996–2000 | 2.20 (1.07–4.50) | 0.93 (0.42–2.06) | 0.85 (0.26–2.80) | 1.07 (0.34–3.35) | 0.90 (0.36–2.29) | 0.78 (0.37–1.63) | 2.31 (1.06–5.01) | 0.95 (0.40–2.26) |
2001–2005 | 3.07 (1.69–5.57) | 2.09 (1.13–3.88) | 0.35 (0.11–1.15) | 0.17 (0.05–0.62) | 1.019 (0.50–2.09) | 1.65 (0.86–3.19) | 3.65 (1.90–7.00) | 2.23 (1.12–4.42) |
2006–2012 | 6.09 (3.11–11.95) | 3.59 (1.87–6.90) | 0.66 (0.22–2.00) | 0.93 (0.42–3.91) | 0.68 (0.31–1.48) | 1.27 (0.63–2.54) | 1.21 (0.63–2.31) | 0.95 (0.49–1.93) |