Table 4 Mean values (95% CI) of EORTC QLQ-H&N35 scores from pretreatment (baseline) to 36 months posttreatment in study- and control patients
Mean (95% CI) Score | |||||||
|---|---|---|---|---|---|---|---|
Scale name | Study population (n = 18) | Controls (n = 18) | p study/control | ||||
Baseline | 6 mo | p | 36 mo | p | |||
Symptom scales | |||||||
Pain | 0.0 (..) | 5.8 (-2.0–13.7) | .25 | 6.5 (-0.4–13.4) | .06 | 3.2 (-1.1–7.5) | .44 |
Swallowing | 8.8 (0.1–17.5) | 4.9 (0.6–9.2) | >.99 | 13.9 (2.2–25.6) | .34 | 8.3 (-0.7–17.3) | .18 |
Senses | 35.2 (21.9–48.5) | 31.4 (18.9–43.8) | .67 | 31.5 (17.9–45.1) | .62 | 7.4 (-1.2–16.0) | .002 |
Speech | 13.6 (6.1–21.1) | 9.2 (4.5–13.8) | .36 | 14.8 (6.3–23.3) | .70 | 13.6 (7.4–19.7) | .76 |
Social eating | 6.0 (0.7–11.3) | 1.5 (-0.2–3.2) | .16 | 13.9 (-0.2–28.0) | .21 | 6.9 (-4.8–18.7) | .16 |
Social contact | 5.9 (1.7–10.2) | 2.8 (-0.9–6.4) | .25 | 5.2 (0.4–10.0) | .88 | 3.0 (-1.9–7.8) | .50 |
Sexuality | 11.1 (3.1–19.2) | 10.8 (1.2–20.3) | .88 | 22.6 (7.1–38.0) | .13 | 39.8 (21.8–57.8) | .02 |
Symptom single items | |||||||
Teeth | 9.3 (-4.4–23.0) | 2.0 (-2.2–6.1) | b | 9.3 (1.6–16.9) | >.99 | 7.4 (-1.7–16.5) | .88 |
Opening mouth | 1.9 (-2.1–5.8) | 3.9 (-1.8–9.6) | a | 9.3 (-3.2–21.7) | .25 | 0.0 (..) | .25 |
Dry mouth | 11.1 (1.3–21.0) | 11.8 (3.3–20.2) | .75 | 16.7 (2.5–30.9) | .38 | 13.0 (1.4–24.5) | .61 |
Sticky saliva | 14.8 (3.1–26.5) | 9.8 (1.8–17.9) | .73 | 22.2 (5.2–39.3) | .36 | 18.5 (5.5–31.5) | .52 |
Coughing | 16.7 (6.4–26.9) | 17.7 (8.8–26.5) | .72 | 16.7 (6.4–26.9) | .72 | 20.4 (7.5–33.3) | .62 |
Felt ill | 3.7 (-4.1–11.5) | 5.9 (-0.9–12.6) | >.99 | 3.7 (-1.7–9.1) | b | 5.6 (-3.0–14.1) | .88 |
Senses scale separated on item level | |||||||
Problems with olfaction | 55.6 (35.1–76.1) | 43.1 (26.3–60.0) | .32 | 44.4 (26.5–62.4) | .30 | 13.0 (-2.2–28.2) | .004 |
Problems with taste | 14.8 (1.8–27.8) | 19.6 (4.7–34.5) | .38 | 17.7 (1.5–33.8) | .68 | 1.9 (-2.1–5.8) | .06 |