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Table 3 Mean values (95% CI) of EORTC QLQ-C30 scores from pretreatment (baseline) to 36 months posttreatment in study- and control patients

From: Effects of total laryngectomy on olfactory function, health-related quality of life, and communication: a 3-year follow-up study

 

Mean (95% CI) Score

Scale name

Study population

(n = 18)

Controls

(n = 18)

p study/control

Norm dataa

 

Baseline

6 mo

p

36 mo

p

   

Functional scales

        

Physical

88.9 (84.2–93.6)

89.4 (83.1–95.7)

.52

85.9 (79.5–92.4)

.31

91.1 (86.3–95.9)

.07

81.6

Role

93.5 (86.5–100.6)

85.3 (76.8–93.8)

.16

86.1 (72.1–100.1)

.28

90.7 (83.1–98.4)

.69

82.6

Emotional

94.9 (90.4–99.4)

90.2 (84.3–96.1)

.09

91.2 (85.6–96.8)

.18

92.1 (85.0–99.3)

.85

88.2

Cognitive

94.4 (90.4–98.5)

97.1 (93.7–100.4)

.25

98.2 (94.2–102.1)

.22

92.6 (85.5–99.7)

.06

85.2

Social

94.4 (88.1–100.9)

90.2 (80.6–99.8)

.53

85.2 (73.2–97.2)

.18

90.7 (83.1–98.4)

.44

89.1

Global QLQ

85.7 (78.9–92.4)

79.4 (69.1–89.7)

.27

80.6 (72.2–89.0)

.12

82.9 (76.4–89.3)

.54

76.4

Symptom scales

        

Fatigue

9.9 (3.6–16.1)

15.0 (6.5–23.6)

.11

14.8 (7.7–21.9)

.14

14.8 (8.8–20.8)

.84

21.5

Nausea and vomiting

0.9 (-1.0–2.9)

1.0 (-1.1–3.1)

.98

1.9 (-0.8–4.5)

.93

0.9 (-1.0–2.9)

b

2.5

Pain

5.6 (-0.8–11.9)

3.9 (0.2–7.7)

.75

13.9 (3.5–24.2)

.11

13.0 (4.2–21.8)

.88

19.2

Symptom single items

        

Dyspnoea

29.6 (20.0–39.3)

33.3 (24.8–41.9)

.25

27.8 (17.5–38.0)

.75

24.1 (14.6–33.6)

.38

23.7

Sleep disturbances

22.2 (5.2–39.3)

19.6 (6.0–33.2)

.95

20.4 (6.3–34.5)

.95

7.4 (-1.7–16.5)

.20

11.8

Appetite loss

1.9 (-2.1–5.8)

2.0 (-2.2–6.1)

b

0.0 (..)

b

1.9 (-2.1–5.8)

b

2.7

Constipation

5.6 (-3.0–14.1)

7.8 (-1.8–17.5)

.50

7.4 (0.3–14.5)

.50

7.4 (0.3–14.5)

.72

6.7

Diarrhoea

0.0 (..)

3.9 (-1.8–9.6)

d

3.7 (-1.7–9.1)

d

5.6 (-0.8–11.9)

>.99

4.2

Financial problems

1.9 (-2.1–5.8)

0.0 (..)

b

0.0 (..)

c

0.0 (..)

>.99

5.4

  1. Abbreviations: CI, confidence interval; EORTC, The European Organization for Research and Treatment of Cancer Core Questionnaire (C30) scale: range per scale: 0–100 where 100 corespond to maximum functioning. Symptom scales and items; where 100 correspond to worst symptoms. Clinically significant change, i.e. a change of ≥10 points.
  2. a Reference values for EORTC QLQ-C30 for 234 men aged 70–79 in the Swedish population drawn from a population-based registry (SEMA) including all Swedish inhabitants born between 1918 and 1979 [11].
  3. b The number of observations after zeros is removed as it is 1 so there is no use calculating the p-value
  4. c The number of observations after zeros is removed as it is 0 so there is no use calculating the p-value
  5. d The number of observations after zeros is removed as it is 2 so there is no use calculating the p-value
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