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Table 4 Diagnoses, Complaints, Quality of Life

From: Homeopathic treatment of patients with chronic sinusitis: A prospective observational study with 8 years follow-up

Status

Baseline

Month 3

Month 12

Month 24

Year 8

Severity (NRS)

Sinusitis ‡

5.88

(5.55; 6.22)

3.11

(2.78; 3.44)

2.11

(1.78; 2.44)

1.63

(1.29; 1.96)

--

Pooled Diagnoses ‡

5.80

(5.50; 6.11)

3.63

(3.32; 3.93)

2.66

(2.36; 2.96)

2.06

(1.75; 2.36)

--

Pooled Complaints †

6.03

(5.70; 6.35)

3.57

(3.22; 3.91)

3.12

(2.86; 3.38)

2.80

(2.52; 3.09)

2.49

(2.13; 2.85)

Quality of Life (SF-36 Component Scores)

Physical †

45.60

(43.42; 47.77)

49.02

(46.75; 51.29)

50.06

(48.09; 52.02)

51.12

(49.08; 53.16)

50.52

(47.97; 53.08)

Mental †

37.08

(35.01; 39.15)

43.96

(41.75; 46.16)

44.43

(42.68; 46.18)

43.86

(41.98; 45.74)

46.92

(44.46; 49.37)

Change

 

Months 0–3

Months 0–12

Months 0–24

Month 0-Year 8

Severity (NRS)

Sinusitis ‡

--

-2.77

(-3.10; -2.45)

-3.77

(-4.17; -3.37)

-4.25

(-4.69; -3.82)

--

Pooled Diagnoses ‡

--

-2.18

(-2.41; -1.94)

-3.14

(-3.45; -2.84)

-3.75

(-4.09; -3.40)

--

Pooled Complaints †

--

-2.46

(-2.82; -2.11)

-2.91

(-3.28; -2.54)

-3.22

(-3.66; -2.78)

-3.49

(-3.97; -3.02)

Quality of Life (SF-36 Component Scores)

Physical †

--

3.43

(1.90; 4.95)

4.46

(2.38; 6.54)

5.53

(2.84; 8.21)

4.74**

(1.31; 8.16)

Mental †

--

6.88

(5.03; 8.72)

7.35

(5.13; 9.57)

6.78

(4.03; 9.53)

9.36

(6.11; 12.62)

Effect Size *

 

Months 0–3

Months 0–12

Months 0–24

Month 0-Year 8

Severity (NRS)

Sinusitis ‡

--

1.58

(1.77; 1.40)

2.15

(2.38; 1.92)

2.43

(2.68; 2.18)

--

Pooled Diagnoses ‡

--

1.56

(1.72; 1.39)

2.25

(2.47; 2.03)

2.68

(2.93; 2.43)

--

Pooled Complaints †

--

1.52

(1.74; 1.30)

1.80

(2.03; 1.57)

1.99

(2.26; 1.72)

2.16

(2.45; 1.86)

Quality of Life (SF-36 Component Scores)

Physical †

--

0.27

(0.15; 0.39)

0.35

(0.19; 0.52)

0.44

(0.23; 0.65)

0.38**

(0.10; 0.65)

Mental †

--

0.66

(0.49; 0.84)

0.71

(0.50; 0.92)

0.65

(0.39; 0.92)

0.74

(0.49; 1.00)

  1. Estimated means and 95% confidence intervals from the statistical model (see text). * Absolute value of Cohen's d, usually classified as |d| > 0.8, large; |d| > 0.5, medium; |d| > 0.2, small. ** p < 0,01, all other non-baseline values p < 0.001. † Patients' answers, ‡ physicians' answers. NRS = Numerical Rating Scale: 10 = maximum, 0 = cured. SF-36 = 36-Item Short Form Survey Instrument, higher values = better.
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