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Table 4 Diagnoses, Complaints, Quality of Life

From: Homeopathic treatment of patients with chronic sinusitis: A prospective observational study with 8 years follow-up

Status Baseline Month 3 Month 12 Month 24 Year 8
Severity (NRS)
Sinusitis ‡ 5.88
(5.55; 6.22)
3.11
(2.78; 3.44)
2.11
(1.78; 2.44)
1.63
(1.29; 1.96)
--
Pooled Diagnoses ‡ 5.80
(5.50; 6.11)
3.63
(3.32; 3.93)
2.66
(2.36; 2.96)
2.06
(1.75; 2.36)
--
Pooled Complaints † 6.03
(5.70; 6.35)
3.57
(3.22; 3.91)
3.12
(2.86; 3.38)
2.80
(2.52; 3.09)
2.49
(2.13; 2.85)
Quality of Life (SF-36 Component Scores)
Physical † 45.60
(43.42; 47.77)
49.02
(46.75; 51.29)
50.06
(48.09; 52.02)
51.12
(49.08; 53.16)
50.52
(47.97; 53.08)
Mental † 37.08
(35.01; 39.15)
43.96
(41.75; 46.16)
44.43
(42.68; 46.18)
43.86
(41.98; 45.74)
46.92
(44.46; 49.37)
Change   Months 0–3 Months 0–12 Months 0–24 Month 0-Year 8
Severity (NRS)
Sinusitis ‡ -- -2.77
(-3.10; -2.45)
-3.77
(-4.17; -3.37)
-4.25
(-4.69; -3.82)
--
Pooled Diagnoses ‡ -- -2.18
(-2.41; -1.94)
-3.14
(-3.45; -2.84)
-3.75
(-4.09; -3.40)
--
Pooled Complaints † -- -2.46
(-2.82; -2.11)
-2.91
(-3.28; -2.54)
-3.22
(-3.66; -2.78)
-3.49
(-3.97; -3.02)
Quality of Life (SF-36 Component Scores)
Physical † -- 3.43
(1.90; 4.95)
4.46
(2.38; 6.54)
5.53
(2.84; 8.21)
4.74**
(1.31; 8.16)
Mental † -- 6.88
(5.03; 8.72)
7.35
(5.13; 9.57)
6.78
(4.03; 9.53)
9.36
(6.11; 12.62)
Effect Size *   Months 0–3 Months 0–12 Months 0–24 Month 0-Year 8
Severity (NRS)
Sinusitis ‡ -- 1.58
(1.77; 1.40)
2.15
(2.38; 1.92)
2.43
(2.68; 2.18)
--
Pooled Diagnoses ‡ -- 1.56
(1.72; 1.39)
2.25
(2.47; 2.03)
2.68
(2.93; 2.43)
--
Pooled Complaints † -- 1.52
(1.74; 1.30)
1.80
(2.03; 1.57)
1.99
(2.26; 1.72)
2.16
(2.45; 1.86)
Quality of Life (SF-36 Component Scores)
Physical † -- 0.27
(0.15; 0.39)
0.35
(0.19; 0.52)
0.44
(0.23; 0.65)
0.38**
(0.10; 0.65)
Mental † -- 0.66
(0.49; 0.84)
0.71
(0.50; 0.92)
0.65
(0.39; 0.92)
0.74
(0.49; 1.00)
  1. Estimated means and 95% confidence intervals from the statistical model (see text). * Absolute value of Cohen's d, usually classified as |d| > 0.8, large; |d| > 0.5, medium; |d| > 0.2, small. ** p < 0,01, all other non-baseline values p < 0.001. † Patients' answers, ‡ physicians' answers. NRS = Numerical Rating Scale: 10 = maximum, 0 = cured. SF-36 = 36-Item Short Form Survey Instrument, higher values = better.