Association of the 4 g/5 g polymorphism of plasminogen activator inhibitor-1 gene with sudden sensorineural hearing loss. A case control study

Table 1 Genotype distribution of PAI-1 polymorphism in SSNHL and controls

Model	Genotype	Controls, n = 113 (Frequency)	SSNHL, n = 103 (Frequency)	OR	95 % CI	χ²	p value
Co-dominant	4 G/5 G	50 (44.2 %)	63 (61.2 %)	1
	4 G/4 G	29 (25.7 %)	24 (23.3 %)	0.66	0.34 – 1.27	1.59	0.210
	5 G/5 G	34 (30.1 %)	16 (15.5 %)	0.37	0.19 - 0.75	7.83	0.005
Recessive	4 G/4 G-4 G/5 G	79 (69.9 %)	87 (84.5 %)	1
Recessive	5 G/5 G	34 (30.1 %)	16 (15.5 %)	0.43	0.22 - 0.83	6.42	0.011

SSNHL sudden sensorineural hearing loss; Odds ratios (OR) with 95 % confidence intervals (CI) and results (p values) of χ² analysis (chi-square test) were calculated for genotype frequencies compared with control.

ISSN: 1472-6815